Dean-
He taught you the basics of martial art fighting for protection since he knows that's the best way to protect you.
Sam-
He'll choose not to go on a hunt when you're sick. Even though you argue with him about it, he always ends up winning.
Cas-
It's like he has a sixth sense when it comes to you. If you get hurt, he's there. If your overly happy, he there to hear the whole story.
Gabriel-
He leaves candy and notes all over the house, and whenever you find one, he'll pop up and give you a kiss on the wrists.