Christine is working as a nurse in Hillview Hospital, a relatively small clinic in an relatively insignificant town. Her seemingly normal work day turns grim, when a patient with an unknown, sinister affliction is rushed to the emergency room. Following this patient's death, things turn grisly as an abhorrent behemoth of flesh and bone bursts from the room, devouring and dismembering anyone in its path. Christine must brave the carnage strewn through the halls in order to save her brother, Jack, who has found himself in a dreadful situation. As they fight for their lives, the gory creature lurks the halls, baring its crimson grin of human teeth.