Mike West as Fox McCloud, James McCloud, ROB64
Alesia Glidewell as Krystal
Mark Lund as Falco Lombardi
Lyssa Browne as Slippy Toad, Katt Monroe
Kath Soucie as Amanda
Catherine Taber as Lucy Hare
Jaz Adams as Peppy Hare, Bill Grey
David Frederick White as Defense Minister Pepper
Michael Bell as Shade Turant, President Thompson
Lex Lang as Vark Krackos
Jay Ward as Wolf O'Donnell, Z-Secs
David Scully as Leon Powalski, Panther Caruso, Elite infantry, Z-Secs
Adam Baldwin as Doug Grissom
Dee Bradley Baker as Pico Sporidian Junior, Karza Borjia, Locust infantry
David Sobolov as Radoven Neigora
Lars Mikkelsen as Lord Synn
Keith Szarabajka as Kronos Kudrov
Nolan North as Dash Bowman, young Doug Grissom
Grant Albrecht as Phantom, Kliment Genden, Dave Grissom, Kig-Yar troopers
David Kaye as Garzan Salazar, Titanian officer
David Zayas as Hugo Zayas
Carlos Alazraqui as Omar Zayas
Noshir Dalal as Imahd Sadat
Steve Blum as Lance Sellik
Mark Hamill as Baphomet, Demon voices
Yuri Lowenthal as young Fox McCloud