Jackson Avery and April Kepner have already gone through enough. When their son, Samuel, dies of type II Osteogenesis Imperfecta, they are heart broken. When they become pregnant with their daughter, they are both overjoyed and terrified. Reassured by Arizona Robbins that their baby is completely healthy, they can finally breath easily. But, when their daughter is born with 5 fractures, and later diagnosed with OI, their world turns upside down. How could a fetal surgeon miss something this big? When they are told that they can file a lawsuit for wrongful birth, things take a turn for the worst. Will Arizona be sued for medical malpractice, or will it all just be a big misunderstanding? Based on the novel Handle With Care by Jodi Picoult.