Victoria Justice as dr. Kaitlyn Reynolds
Chris Pine as Joshua Paxton
Amanda Seyfried as dr. Bethany Graham
Austin Butler as Noah Graham
Diana Korkunova as dr. Jenifer Rhee
Matthew Gray Gubler as dr. Isaac Baker
Tyler Posey as dr. Thomas Cooper
Courtney Cox as Renee Reynolds
Dylan O'Brien as Cole Reynolds
Dennis Quaid as Peter Paxton
Julia Roberts as Irene Paxton
Helen Mirren as Margaret Paxton
Cameron Diaz as dr. Laura Reed
Theo James as dr. Charles White