He's upset.
Dean- You know when he is upset when he looks like he is constantly beating himself up, mentally. You cam sometimes hear him talk to himself.
Sam- He is always talking to himself about the problem. When he hugs it is not the usual. Then you know he is upset.
Cas- He just mopes around, like there is nothing to live for. He is slouching and he drags his words.
Gabriel- He could sleep all day if he could but he just stay in his bed lying face down and he moans.
Balthazar- He drowns his sadness in wine. Too many wine and you know he just drowning them away.
Lucifer- He take his sadness into anger.
Michael- He starts hyperventilating because he can't contain his calmness about his sadness. (Does that even makes sense.)
Crowley-His Sadness is noticeable. Well, he just comes in and announced it.