I have headcanon that if Dean ever met Jensen in real life he would just laugh at him and at his life until he saw Danneel. And then his mouth would fall open and he'd be like 'never mind, you done good'
I feel like Sam would just be kind of weirded out by Jared because Jared is such a deeply hyperactive puppy man. But you can't just not love Jared so I feel like Sam would be biffles by the end of it.
Cas would just have no idea how to deal with Misha. It would be beautiful. It would be like a puppy meeting an owl.
€5 says Misha would hit on Cas for fun.
€10 says Misha would make Castiel feel as uncomfortable as he makes everyone else feel.
"I don't understand why you're so close. Could you step back a little? You should talk to Dean about personal space. He can explain it. Misha? Misha please. Remove your finger from my nose. This isn't funny"
