To achieve this method of murdering our most hate-able main character, you will need to buy a bomb from some dodgy man at the back of the chippie and stick it in her underwear. Then you pull her pants over her face - which are clearly a viable defence method - and watch as she explodes.
I hate Adrienne.
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10 Way to Kill Adrien - a Spin off of Panacea
Spiritual10 ways to kill the most annoying protagonist of all time