The cell membrane (plasma membrane) is a thin semi-permeable membrane that surrounds the cytoplasm of a cell. Its function is to protect the integrity of the interior of the cell by allowing certain substances into the cell, while keeping other substances out. It also serves as a base of attachment for the cytoskeleton in some organisms and the cell wall in others.
Another function of the membrane is to regulate cell growth through the balance of endocytosis and exocytosis. In endocytosis, lipids and proteins are removed from the cell membrane as substances are internalized. In exocytosis, vesicles containing lipids and proteins fuse with the cell membrane increasing cell size.
The cell membrane is primarily composed of a mix of proteins and lipids. Depending on the membrane’s location and role in the body, lipids can make up anywhere from 20 to 80 percent of the membrane, with the remainder being proteins.
The cell membrane contains two types of associated proteins. Peripheral membrane proteins are exterior to and connected to the membrane by interactions with other proteins. Integral membrane proteins are inserted into the membrane and most pass through the membrane. Portions of these transmembrane proteins are
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