Just thought I'd put a cast list of the main characters in this, if for some reason you've came onto this without knowing who everyone is.... (there'll more than likely be more characters than this, but these are the main ones that'll show up. I may add to this cast list at a later date when other characters appear)
These pictures and gifs are a mixture of the seasons. Will try and state what episode and season they're from. I'd say I'm pretty good at placing photos and scenes with episodes and seasons (I've watched the show too many times....) not quite the cold openings though....
I tried to find gifs for each, but there's not a hell of a lot of decent gifs for the show....
Frankie Muniz as Malcolm Wilkerson
(Image from season 7, episode 2; Health Insurance)
Justin Berfield as Reese Wilkerson
(Image from season 7, episode 22; Graduation)
Erik Per Sullivan as Dewey Wilkerson
(Image from season 6, episode 5; Kitty's Back)
Bryan Cranston as Hal Wilkerson
(Image from season 1, episode 13; Rollerskates)
Jane Kaczmarek as Lois Wilkerson
(Image from cold opening of season 6, episode 20; Stilts)
Lukas & James Rodriguez as Jamie Wilkerson
(Image from season 7, episode 7; Blackout)
(BTW, Jamie was played by twins, but I'm not sure which twin this photo is)
Emy Coligado as Piama Wilkerson (neé Tananahaakna)
Christopher Kennedy Masterson as Francis Wilkerson
(Image from season 7, episode 15; A.A.)
Craig Lamar Traylor as Stevie Kenarban
(Image from season 6, episode 9; Malcolm's Car)
David Anthony Higgins as Craig Feldspar
(Image from season 2, episode 7; Robbery)
Hayden Panettiere as Jessica
(image from season 7, episode 5; Jessica Stays Over (I think? Need to check))
Cloris Leachman as Ida
(image from season 6, episode 14: Ida Loses A Leg)
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Extra Cast
(just cause I plan on writing a few one-shots where the boys are girls)
Lisa Foiles as Mallory Wilkerson
Jennette McCurdy as Daisy Wilkerson
Mimi Paley as Renee Wilkerson
(Image from season 4, episode 10; If Boys Were Girls)
Christopher Kennedy Masterson as Frances Wilkerson
(Image from season 4, episode 10; If Boys Were Girls)
......