A man in the late '30s realize that he has a rare disease and his body is weak. Migraine and chest pain, fatigue and weakness with struggles of life make his marriage loveless. His wife feels he is cheating on her and him on the other side don't want a second child. He has his desires but his wife is not satisfying him. He loves his wife a lot and doesn't want to cheat her. He meets his school friends and pretends to be a happily married guy. His daughter is his world. In frustration, he is now attracted to his school friend Riya. Will she fall for her after her failed marriage? Kehne ko Humsafar hein is both their weakness.