Avery Hope is NOT your average teenager. She has a strong disliking of everyone else her age, and is always trying to be different from everyone in her school. She only has one friend, Simon, and their friendship mainly consists of a comfortable silence and reading comic books. When Charlie, a seemingly average person, transfers to her school, Avery just sees him as just another person to dislike. However, when they become lab partners, Avery learns he has terminal skin cancer and is also insociable. Soon, Charlie becomes friends with Simon and Avery, However, soon, it becomes apparent that Charlie hasn't got much time left. Together, they devise a bucket list of things they have all wanted to experience, and set out to complete it as fast as they can before time runs out for Charlie.