Spider-Verse: Web of Enemies
What happens when you put together 5 different Spider-Mans from entirely different universes?
Six of Spider-Man's greatest villains have come together and completely destroyed New York City, posing a threat that will call for not one Spider-Man, but five of them: Tobey Maguire's Spider-Man, Andrew Garfield's Spider-Man, Tom Holland's Spider-Man, Miles Morales, and Spider Gwen.
Combining their spider-powers, they will need to defeat this "Sinister Six" before multiple dimensions are destroyed.
This takes place about a couple months after "Spider-Man: Homecoming" and is still canon with the MCU (or at least my version of it).