Luke Blake is a firefighter; everyday he risks his life to rescue other people. He is in and out of relationships and he can never seem to hold interest in the women he is with. That was until they were called out to an apartment building, he watched as a young woman ran into the building to try and save her family. He is an amazement of this woman and is even surprised when the next day she is the new paramedic at firehouse 17. When Mia Peters is trying to start a new life, she makes a promise to herself never to get close to anyone again. Mia is broken, coping day by day with secrets she's willing to take to the grave. As always, nothing stays a secret for long.