Anastasia is a vampire, who was turned by Katherina Petrova. She has been on the run from Klaus and Katherina ever since for 400 years. In 1864, Anastasia decided to settle down in Mystic Falls for a few years. A man named Giuseppe Salvatore allowed her to stay with him. There she meets the Salvatore brothers. Damon and Anastasia become bestfriends and Anastasia begins to fall in love with Stefan and vice versa. The two begin a romantic relationship until Kathrine shows up forcing Anastasia to leave. Over a hundred years later, Anastasia hears word that Damon Salvatore had became a vampire and had been alive this entire time and is now back in Mystic Falls. She goes back to Mystic Falls to reunite with her bestfriend. There she runs into Stefan who also is a vampire. Will their love be rekindled? Or will Stefan Salvatore remain with the beautiful doppelgänger of Katerina Petrova, Elena Gilbert?