Everything changes for America when she falls through a star shaped portal, a dead sorcerer supreme and one-eyed tentacled monster inches behind her, into Universe 616. Alone in a universe where the only people she knows are another Doctor Strange and a different Sorcerer Supreme who had saved her. Frightened by the last Doctor Strange she knew, America runs. But how long can she run when she's on her own with powers she still doesn't understand? Can America learn to trust a Doctor Strange again enough to accept his help or will she find someone new to put her trust in?