Impotence in men is associated with general health status, thus, lifestyle modification shall enhance penile function and might lower the rate of decline of function along with age. One year after discontinuation of smoking, patients were later found to have a 25% improvement in penile erection quality even while consuming Manforce. In addition, the multivariate analysis had also found that obesity is also directly associated with impotence with an approx. 50% enhancing in ED in obese men as compared to normal weighing men.
Over a 2-year period, one-third of the men randomized to some effective weight loss program demonstrated resolution of impotence. A Mediterranean diet and some sort of nutritional counseling reported enhancing erectile quality. Little evidence shall eventually support that enhanced physical activity alone and might help in improving erectile quality; however, the strong association that lies between physical activity and lower BMI is described, and therefore it is highly recommended for men with impotence and without a contraindication to any of the physical activity.
As per a review of all randomized controlled trials, while evaluating Sildenafil Citrate composed Manforce by the American Urological Association (AUA) Consensus Panel impotence, 36% to 76% of men who are receiving this drug were able to achieve intercourse during treatment. For other impotence treating medicine four randomized controlled trials revealed that 11% to 47% of men were "able to play for a longer lovemaking session."
A similar kind of efficacy has been observed with other ED medicine, although studies are fewer. A meta-analysis that was published in 2013 clearly demonstrated increased efficacy over placebo for all PDE5 inhibitors. Head-to-head comparison has been suggested that Tadalafil outperforms Sildenafil Citrate (Manforce) on validated measures of impotence, including the international index of penile function and sexual encounter profile-2 and -3. Medicine does the job well when consumed in the presence of complete sexual arousal.