In a desolate apartment complex on the outskirts of Rome, Anna's life is upended when her partner, Lorenzo, is found dead while working as a driver for the famous comedian Mauro Piazza. As Anna grapples with her grief, she crosses paths with Bianca, Mauro's enigmatic widow, and Margherita, a resilient bar owner whose son, Ivan, discovered the bodies. "Blu River" weaves together the stories of these three women, each facing unexpected tragedies that force them to confront their deepest fears and darkest secrets. Through loss and newfound strength, their lives intersect in ways that reveal the fragile connections holding them together.